The 6th International Conference on Biomedical Engineering and Biotechnology (ICBEB 2017)
October 17th - 20th, 2017, Guangzhou, China
• 中文版     • English
Invited Speaker ---- Dr. Haiyan Zhou

Professor, Hainan Medical College School of Dental Medicine
Director of the Central Laboratory, the First Affiliated Hospital of Hainan Medical College, China

Speech Title: Identification of Hydroxyapatite-Interacting Proteins in Bone
Abstract: Biomineralization involves proteins directly in controlling the mineral crystal nucleation/induction, growth, and maturation. We have identified these ~30 proteins in bone (Ann N Y Acad Sci. 2007 Nov;1116:323-326). In the present study ~20 additional proteins were identified by chromatography on a DE-52 column to separate basic/neutral and acidic proteins followed on a hydroxyapatite column in combination with mass spectrometry. Prominent among the newly identified hydroxyapatite-interacting proteins are extracellular matrix proteins such as collagen types V and X, bone sialoprotein, osteopontin and versican, cell growth and differentiation factors pleiotrophin and γ interferon, etc., indicating that the mineral crystals are regulated by the specific proteins secreted by bone cells and in turn can affect the cells via their proteins.

The 6th International Conference on Biomedical Engineering and Biotechnology
Conference Secretary: Linda Li
Email: icbeb@icbeb.org   Tel: +86-27-87051286
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