Associate Professor, Faculty of Applied Sciences, University of West Bohemia, Czech

Speech Title: Development of the Diffusion Model of Glucose Dynamics
Abstract: Diabetes is a silent civilization disease. It is 8 th most common cause of death. 1 in 11 adults have diabetes and 46.5% of them are undiagnosed. Specifically, diabetes is a heterogeneous group of disorders that share a common phenotype of elevated blood glucose level. Over the long-term, it is associated with damage to various organs and their failure. Engineering is integral to diabetes treatment – from glucose measuring to artificial pancreas (which requires the measuring). There is a system of continuous glucose level monitoring in subcutaneous tissue. Using a model of glucose dynamics, we can transform this continuously measured glucose level into a continuous blood glucose level. This improves assessment of patient’s condition as it is unfeasible for the patient to conduct continual measuring of blood glucose level. In this paper, we focus on the development of the diffusion model of glucose dynamics. We derive the model from its base considerations up to its extended form, while following the original path of its development. Hence, the following researches get a consistent of view on the model. We compile the published papers into a compact perspective, while adding complementary hints and notes.